Under greenhouse and field conditions all tested inducers significantly reduced damping-off, root and pod rot incidence. In this respect salicylic acid at 4 mM followed by hydrogen peroxide at 0.25% gave the highest effect on all parameters of disease incidence and consequently increasing percentage of healthy survival plants. Increasing concentration of salicylic acid up to 4 mM and hydrogen peroxide up to 0.25 % led to a decrease in their effect on reducing the disease incidence. While, effect of bion on reducing of diseases incidence increased with increasing of their concentrations. Results also stated that, there is a correlation between induced resistance and some biochemical changes in roots tissues like increased the activity of oxidative enzymes (catalase, peroxidase and polyphenoloxidase) and accumulation of phenol compounds. Salicylic acid at 4 mM followed by bion at 8 mM. recorded the highest content of phenol compounds while, the highest increase of activity of oxidative enzymes (catalase, peroxidase and polyphenoloxidase) in roots of peanut plants recorded with salicylic acid at 4 mM and hydrogen peroxide at 0.25 %. There are new protein bands and others increased in their intensity because of chemical inducers treatments. Bion at 4 and 8 mM, hydrogen peroxide at 0.25 % gave a new protein bands with MW 29, 48 and 54 KD. Salicylic acid treatment in all concentrations showed participation in a new protein band MW 22 KD. While, salicylic acid at 2 and 4 mM participation in a new protein band with hydrogen peroxide at 0.5% and 1% (MW 55 KD). In the same time hydrogen peroxide at their all concentration gave a new protein band with MW 34 and 36 KD.