Curriculum Vitae

Prof. Dr. Nahla Sayed Abdel-Azim

PERSONAL DETAILS:

Surname: Abdel-Azim

Other names: Nahla Sayed

Title:  Prof. Dr.

Gender: Female

Address:  National Research Centre, 33 El Bohouth St. (former El Tahrir st.), Dokki, Giza, Egypt

Post Code: 12622

Mobile: 0127456703

Email: [email protected]

Date of birth: 08.11.1962

Place of birth: Giza, Egypt

EDUCATION:

<!--Ph.D. in Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt (1991-1996).

<!--M.Sc. in Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt (1988-1991).

<!--B.Sc. in Chemistry (very good), Faculty of Science, Cairo University, Cairo, Egypt (1980 – 1984).

SEMINARS, WORKSHOPS AND TRAINING:

<!--Participated in International DAAD Alumni Expert Seminar "Hidden Hunger", 12-19 March 2017 in Giessen.

<!--Participated in International DAAD Alumni Seminar "Do we feed the world? Local and global perspectives on sustainable agricultural incentives" in the run-off to the BioFach trade fair 2016, from 2- 13 February 2016 at the Georg-August University Göttingen, Germany.

<!--Participated in workshop on HPTLC, (Basel, Switzerland, 2012)

<!--Participated in workshop on solar energy in MENA region organized by DESERTEC and DAAD (Giessen, Germany, 2011)

<!--Participated in workshop on proposal writing, (Cairo, Egypt, 2009)

<!--Participated in a workshop on « Management des Questions Environnementales et l’Energie Solaire »  qui se tiendra à Yaoundé au Cameroun du 17 au 21 Novembre (2008).

<!--Participated in workshop on project management organized by DAAD, (Cairo, Egypt, 2006).

<!--Participated in workshop on strategic thinking organized by DAAD, (Cairo, Egypt, 2005).

<!--Participated in a workshop on Intellectual Property Rights, (Masstricht, Holland, 2000)

<!--Participated in Logical Framework Approach (LFA) planning workshop for the preparation of the large-scale project in the field of conservation of medicinal plant species in Egypt, organized by UNDP (1999).

<!--Participated in a workshop on "Biological Evaluation of Medicinal Plants", CDRI, Lucknow, India, (1997).

<!--Participated in a training course on "TLC advanced techniques", Anchrom, Mumbai, India, (1997).

<!--Ph.D. student at the institute of Pharmaceutical Biology, Albert Lüdwigs University, Freiburg, Germany.

<!--Participated and successfully completed two training course in "Modern NMR Techniques; basis and applications in structural elucidation", Cairo University, Egypt, (1996), (1998).

<!--Visitor Researcher in Biochemistry Dept., University College of Swansea, Swansea, Wales, United Kingdom (1990-1991).

EMPLOYMENT HISTORY:

<!--Head of Phytochemistry Dept.

<!--Professor in NRC: from  31/1/2010    till now.

<!--Associate Professor in NRC: from  31/1/2005    to    30/1/2010.

<!--Researcher in NRC: from   16/7/1996    to    31/1/2005

<!--Assistant Researcher in NRC: from    28/11/1991   to    16/7/1996

<!--Researcher Assistant in NRC: from 31/7/1988   to 28/11/1991  

MEMBERSHIP OF PROFESSIONAL ASSOCIATIONS:

<!--Member of Medicinal Ethics Committee, National Research Centre (2015-now).

<!--Member of National Committee of Women in Science, Academy of Scientific Research and Technology (2012-now).

<!--Member of Scientific Ethics Committee, Academy of Scientific Research and Technology (2012-2015).

<!--Member of Gessellschaft für Arzneipflanzenforschung (Society for Medicinal Plant Research).

<!--Member of the Arab Society for Medicinal Plants.

<!--Member of the Scientific Association for Egyptian women.

FIELDS OF INTEREST:

<!--Extraction of oils from plants.

<!--Phytochemical screening of medicinal plants.

<!--Isolation and identification of natural products using the different chromatographic techniques.

<!--Interpretation of spectral data with special emphasis to NMR analysis

<!--Pharmacological screening of medicinal plants

<!--Conservation and sustainable use of wild medicinal plants

<!--Traditional medicine and knowledge

PUBLICATIONS AND PATENTS:

PUBLICATIONS

1. Ibrahim Ahmed Saleh, Mircea Vinatoru, Timothy James Mason, Nahla S. Abdel-Azim, Khaled A. Shams, Elsayed Aboutabl & Faiza M. Hammouda. Extraction of silymarin from milk thistle (Silybum marianum) seeds– a comparison of conventional and microwave-assisted extraction methods. Journal of Microwave Power and Electromagnetic Energy, VOL. 51, NO. 2, 124–133 (2017).

2. I. A. Saleh, M. Vinatoru, T.J. Mason, N.S. Abdel-Azim, E.A. Aboutabl, F.M. Hammouda. "A possible general mechanism for ultrasound-assisted extraction (UAE) suggested from the results of UAE of chlorogenic acid from Cynara scolymus L. (artichoke) leaves" Ultrasonics Sonochemistry, 31: 330–336, (2016).

3. Ibrahim Ahmed Saleh, Mohamed-Elamir Fathy Hegazy, Tarik Abdelhalim Mohamed, Khaled Ahmed Shams, Elsayed Aboutabl, Nahla Sayed Abdel-Azim and Faiza Mohamed Hammouda. Evaluation of accelerated solvent extraction (ASE) for obtaining chlorogenic acid from Cynara scolymus L. (artichoke) leaves. Analele Stiintifice ale Universitatii "Al. I. Cuza" din Iasi, 62(1), 94 (2016).

4. Hegazy ME, Mohamed TA, Elshamy AI, Hassanien AA, Abdel-Azim NS, Shreadah MA, Abdelgawad II, Elkady EM, Paré PW ‘’A new steroid from the Red Sea soft coral Lobophytum lobophytum‘’ Natural Product Research, 30 (3): 340-344 (2016).

5. Hamed AR, Hegazy MF, Higgins M, Mohamed TA, Abdel-Azim NS, Pare PW, Dinkova-Kostova AT. Potency of extracts from selected Egyptian plants as inducers of the Nrf2-dependent chemopreventive enzyme NQO1. Journal of Natural medicine, 70 (3), 683-688, (2016).

6. Hegazy ME, Ibrahim AY, Mohamed TA, Shahat AA, El Halawany AM, Abdel-Azim NS, Alsaid MS, Paré PW. Sesquiterpene Lactones from Cynara cornigera: Acetyl Cholinesterase Inhibition and In Silico Ligand Docking. Planta Med. 82(1-2):138-46 (2016).

7. Khaled A. Shams, Nahla S. Abdel-Azim, Ibrahim A. Saleh, Mohamed-Elamir F. Hegazy, Mostafa M. El-Missiry and Faiza M. Hammouda. " Green technology: Economically and environmentally innovative methods for extraction of medicinal & aromatic plants (MAP) in Egypt" Journal of chemical and pharmaceutical research. 7(5): 1050-1074 (2015).

8. Khaled A. Shams, Nahla S. Abdel-Azim, Wafaa A. Tawfik, Heba D. Hassanein, Mahmoud A. Saleh and Faiza M. Hammouda. "Green Extraction Techniques: Effect of Extraction Method on Lipid Contents of Three Medicinal Plants of Apiaceae" Journal of chemical and pharmaceutical research. 7(4):1080-1088 (2015).

9. Khaled A. Shams, Nahla S. Abdel-Azim, Sherin A Kamal, Husseiny A. Husseiny and Faiza M. Hammouda. "Green Extraction: Enhanced Extraction Yield of Glycyrrhizic Acid from Glycyrrhiza glabra L." Journal of chemical and pharmaceutical research. 7(4):725-728 (2015).

10. Ibrahim A Saleh, Sherin A Kamal, Khaled A Shams, Nahla S Abdel-Azim, Elsayed A Aboutabl and Faiza M Hammouda. "Effect of Particle Size on Total Extraction Yield and Silymarin Content  of Silybum marianum L. Seeds". Research Journal of Pharmaceutical, Biological and Chemical Sciences, 6(2): 803-809 (2015).

11. Hassanein, H.D.,  Abdel Mohsen, M.M.,  Shams, K.A.,  Abdel-Azim, N.S.,  Saleh, M.A.,  Ehsan, N.A.,  Hammouda, F.M. Comparative analysis of biological activity of Silybum marianum L. Food supplements available on market: In vitro study. International Journal of Pharmacy and Pharmaceutical Sciences, 7 (11): 55-60 (2015).

12. Hegazy, M.E.F. <!--<!-- ,  Mohamed, T.A.,  ElShamy, A.I.,  Mohamed, E.H.H.,  Mahalel,U.A.,  Reda, E.H.,  Shaheen, A.M.,  Tawfik, W.A.,  Shahat, A.A.,  Shams, K.A.,  Abdel-Azim, N.S.,  Hammouda, F.M. Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review. Journal of Advanced Research, 6 (1): 17-33 (2015).

13. Hegazy, M.-E.F. <!--<!-- ,  Nakamura, S.,  Tawfik, W.A.,  Abdel-Azim, N.S.,  Abdel-Lateff, A.,  Matsuda, H.,  Paré, P.W. Rare hydroperoxyl guaianolide sesquiterpenes from Pulicaria undulata. Phytochemistry Letters, 12:177-181 (2015).

14. Hegazy, M.-E.F. <!--<!-- ,  Mohamed, T.A.,  Elshamy, A.I.,  Hassanien, A.A.,  Abdel-Azim, N.S.,  Shreadah, M.A.,  Abdelgawad, I.I.,  Elkady, E.M.,  Pare, P.W. A new steroid from the red sea soft coral lobophytum lobophytum. Natural Product Research, 30 (3): 340-344 (2015).

15. Hegazy, M.-E.F.,  Ibrahim, A.Y.,  Mohamed, T.A.,  Shahat, A.A. <!--<!-- ,  El Halawany, A.M.,  Abdel-Azim, N.S.,  Alsaid, M.S.,  Paré, P.W. Sesquiterpene Lactones from Cynara cornigera: Acetyl Cholinesterase Inhibition and in Silico Ligand Docking. Planta Medica, 82: (1-2) 138-146 (2015).

16. Ibrahim Ahmed Saleh, Khaled Ahmed Shams, Wafaa Abdel-monaem Tawfik, Amira Abdel-azim Habib, Rasmia A Hassan, Abdelaaty Abdelaziz Shahat, Elsayed Ahmed Aboutabl, Faiza Mohamed Hammouda, Nahla Sayed Abdelazim. "Investigation of the lipid and carbohydrate contents of Grewia tenax forssk. fruits & evaluation of hepatoprotection activity" International Journal of Pharmacy and Pharmaceutical Sciences, l 7 (5): 179-182 (2015).

17. IA Saleh, M Vinatoru, TJ Mason, NS Abdel-Azim, EA Aboutabl, and FM Hammouda.  "Ultrasonic-Assisted Extraction and Conventional Extraction of Silymarin from Silybum marianum seeds; A Comparison". Research Journal of Pharmaceutical, Biological and Chemical Sciences, 6(2): 709-717 (2015).

18. Mohamed-Elamir F Hegazy, Tarik A Mohamed, Abd El-Samid I El-Shamy, H Mohamed Abou-El-Hamd, Usama A Mahalel, Eman H Reda, Alaa M Shaheen, Wafaa A Tawfik, Abdelaaty A Shahat, Khalid A Shams, Nahla S Abdel-Azim, Fayza M Hamouda “Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review” Journal of Advanced Research, 6(1), 17-33 (2015).

19. Faiza M. Hammouda, Mahmoud A. Saleh, Nahla S. Abdel-Azim, Khaled A. Shams, Shams I. Ismail1, Abdelaaty A. Shahat and Ibrahim A. Saleh “Evaluation Of The Essential Oil Of Foeniculum Vulgare Mill (Fennel) Fruits Extracted By Three Different Extraction Methods By GC/MS” Afr. J. Tradit. Complement. Altern. Med. 11(2):378-380 (2014).

20. Safaa H Mohamed, Hanaa H Ahmed, Abdel Razik H Farrag , Nahla S Abdel-Azim, Abdelaaty A Shahat "Cynara scolymus for Relieving on Nonalcoholic Steatohepatitis Induced in Rats"  International Journal of Pharmacy and Pharmaceutical Sciences,5(1), 57-66 (2013).

21. Mona A. Abou Elfotoh, Khaled A. Shams, Kevin P. Anthony, Abdelaaty A. Shahat, Magda T. Ibrahim, Nevein M. Abdelhady, Nahla S. Abdel Azim, Faiza M. Hammouda, Mostafa M. El-Missiry and Mahmoud A. Saleh. "Lipophilic Constituents of Rumex vesicarius L. and  Rumex dentatus L." Antioxidants, 2, 167-180 (2013).

22. Nahla S. Abdel-Azim, Khaled A. Shams, Abdel-Aaty A. Shahat, Mostafa M. El-Missiry, Shams I. Ismail and Faiza M. Hammouda. "Egyptian Herbal Drug Industry: Challenges and Future Prospects", Research Journal of Medicinal Plant, 5 (2): 136-144, (2011).

23. I. A. Saleh, N.S. Abdelazim, K. A. Shams, A. A. Shahat, F. M. Hammouda and E. A. Aboutabl. "Flavonoidal Components, Volatile Constituents and Antioxidant Activity of Grewia tenax Forssk. (Tiliaceae) Fruits", Egyptian Pharmaceutical Journal, 9 (2), 95-104, (2010).

24. Taha H. S., Farag H.S., Shams A. K. , Abdel-Azim S.N., Hanna G. A., Ewais E. E. and Seif El-Nasr M. M. “In vivo and in vitro studies on Thevetia Species Growing in Egypt I: Isolation, Identification, and Quantification of cardiac glycosides in in vivo and in vitro cultures of immature seeds”, Journal of American Science; 6(11), 390-395, (2010).

25. Khaled A.Shams, Naglaa M. Nazif, Nahla S. Abdel Azim, KHaled A. Abdel Shafeek, MostafaM. El-Missiry, Shams I. Ismail, Medhat M. Seif El Nasr. "Isolation and Characterization of  Antineoplastic Alkaloids from Catharanthus roseus L. Don. Cultivated in Egypt."Afr. J. Trad. CAM 6 (2): 118 – 122, (2009).

26. Wafaa A. Tawfik, N.S. Abdel-Azim, Abdelaaty A. Shahat, N.M. Hassan, S. I. Ismail and F.M. Hammouda, Chemical Investigation of Opuntia tuna Growing in Egypt, Australian Journal of Basic and Applied Sciences, 3(1): 96-102 (2009).

27. W.A. Tawfik, K.A. Shams, N. S. Abdel-Azim, N.M. Hassan and S.I. Ismail, Naphthaquinons of Alkanna orientalis (L.) Boiss., Afr. J.Trad. Comp. Alt. Medicine, 4(1): 55-58 (2007).

28. A.A. Habib, N.S. Abdel-Azim, K. A. Shams and N. M. Hassan, Evaluation of Narcissus tazetta under different habitats, Asian Journal of Chemistry, Vol. 19, No. 6, pp. 4586-92 (2007).

29. A.R. Hamed, K.A. Abdel-Shafeek, N.S. Abdel-Azim, S. I. Ismail and F.M. Hammouda, Chemical investigation of some Capparis species growing in Egypt and their antioxidant activity, eCAM, 4 (S1): 25-28 (2007).

30. Samia M. Mahmoud, N.S. Abdel-Azim, Abdelaaty A. Shahat, S. I. Ismail and F.M. Hammouda, Phytochemical and Biological Studies on Verbascum sinaiticum Growing in Egypt. Natural Product Sciences, 13(3): 186-189 (2007).

31. K.A. Shams, N. S. Abdel-Azim, S.I. Ismail and F.M. Hammouda, Evaluation of Carotenoids from Bixa orellana cultivated in Egypt as a natural colorant, Bull. NRC, Vol. 31, No. 5, pp. 385-397 (2006).

32. S.A. El Batran, N.S. Abdel-Azim, K.A. abdel-Shafeek, A.A. Shahat and M.M. El-Missiry, Flavonoids of Gomphocarpus sinaicus and Evaluation of some Pharmacological Activities, Journal of Pharmaceutical Sciences, 11(4): 233-239 (2005).

33. A.A. Shahat, N.S. Abdel-Azim, L. pieters and A.J. Vlietinck. Isolatin and NMR Spectra of Syringaresinol-B-D-Glucoside from Cressa cretica. Fitoterapia, 75, 771-773 (2004).

34. Abdelaaty A. Shahat, Luc Pieters, Sandia Apers , Naglaa M. Nazif, Nahla S. Abdel Azim, Dirk Vanden Berghe and Arnold J. Vlietinck. Chemical and Biological Investigations on Ziziphus Spina Christi, Phytotherapy Research, 15, pp. 593-597, (2001).

35. Nahla S. Abdel-Azim, A Cardnolide Glycoside from Gomphocarpus sinaicus, Phytochemistry, 49, NO.1, pp. 273-275, (1998).

36. Nahla S. Abdel-Azim, Faiza M. Hammouda and Horst Rimpler, Re-investigation of the Cardenolide Glycosides from Gomphocarpus sinaicus; Phytochemistry, Vol. 42, No. 2, 523-529, (1996).

GRANTS/ AWARDS:

<!--Awarded "Professor Faiza M. Hammouda Scientific Recognition Prize (In Phytochemistry) "(2008).

<!--DAAD Grant as Ph.D. student at the institute of Pharmaceutical Biology, Albert Lüdwigs University, Freiburg, Germany (1993-1995).

Administrative Experience:

<!--Head of Phytochemistry Dept. for the second time.

<!--Member of the Technical Office at the National Research Centre (1999-2000).

<!--Member of the Technical Committee of the Supreme Council for Research Centers and Institutes (2004-2008).

<!--Participating in organizing an International Workshop on "Medicinal Plants and Liver Diseases" at the National Research Centre under the auspice of Prof. Hany El-Nazer.

<!--Participating in organizing a Workshop on (Planar Chromatography "Modern Instrumental TLC) at the National Research Centre (2006).

Research Projects:

<!--"Cultivation, Post-Harvest Processing and Marketing Support of Egyptian Medicinal Plants" between the NRC and Academy of Scientific Research and Technology (2015-present).

<!--"Preparation of Encyclopedia of Egyptian wild Medicinal Plants" between the NRC and Academy of Scientific Research and Technology (2015-present), Co-PI.

<!--“Novel Phytochemical components from some Egyptian flora for the treatment of Viral Hepatitis C - “Genotype 4” ID: 4549 - US EGYPT Grant between STDF and National Research Centre (2011-present).

<!--"Development of a Natural Product for the treatment or/and control of Hepatitis C Virus (HCV) infection" between Industrial modernization center, National Research Centre and Academy of Scientific Research and Technology (2008-2010).

<!--“Development of a Natural Product as Potential Sources of Lead Compounds for Fatty Liver” between STDF and National Research Centre (2009- 2011).

<!--"Economically and Environmentally Friendly Innovative Techniques for Extraction and Isolation of Medicinal and Aromatic Plants (MAP) of Egypt: A Technology Transfer Proposal (Phase I)" between STDF and National Research Centre (2010-2014).

<!--إدخال التكنولوجيات الحديثة المناسبة والأستفادة منها فى تنمية المرأة فى قرية بنى روح بمحافظة المنيا (على نطاق أسرى ومجتمعى) (2010).

<!--"Evaluation of Medicinal Plants in the Treatment of Anemia" between NRC and ASRT (2007-2009), PI.

<!--"National Surveys of Wild Medicinal Plants" between the National Research Centre Egypt and the Egyptian Environmental Affairs Agency (EEAA), United Nations Development Programme (UNDP) and Global Environmental Facility (GEF) (2004-2006).

<!--“Evaluation of Egyptian Medicinal Plants for their Biological Activities” between the NRC and Academy of Scientific Research and Technology (1998-2002).

<!--“Conservation and Sustainable Use of Medicinal Plants in Arid and Semi-arid Ecosystems of Egypt” (St. Katherine-Sinai) between the Egyptian Environmental Affairs Agency (EEAA), United Nations Development Programme (UNDP) and Global Environmental Facility (GEF) (2000-2004).

<!--“Industrialization of natural food additives" between the NRC and Academy of Scientific Research and Technology (1999-2002).

<!--“National Encyclopedia on Phytochemistry of Wild Plants Growing in Egypt” between the National Research Centre Egypt and Academy of Scientific Research and Technology (1999).

<!--“Color and Flavour Additives from Natural Resources” between the NRC and Academy of Scientific Research and Technology from (1995-1998).

<!--“Modified Techniques for Cultivation of Certain Medicinal Plants in new Re-claimed Lands as Sources of Biologically Active Agents” between the NRC and the National Agricultural Research projects NARP from (1992-1994).

<!--“Development and Utilization of Medicinal Plants in Sinai” between the NRC and Academy of Scientific Research and Technology and Suez Canal University (1985-1988).

<!--Color Additives from Natural Resources” between the NRC and Academy of Scientific Research and Technology from (1984-1988).

Published Books

<!--"Development of a Natural Product for the Treatment or / and Control of HCV Infection", Lambert Academic Publishing (in press).            

<!--Egypt Green Technologies for Extraction of Egyptian Medicinal Plants" LAMBERT Academic Publishing, Germany, 2015.

<!--Quality and Standard Specifications (Co-author), Published by Supreme Council for Research Centers and Institutes, 2008.

<!--Traditional, Complementary and Alternative Medicine between Science and Public (Co-author), Published by Supreme Council for Research Centers and Institutes, 2008.

<!--Quality Control of Medicinal Plants (Co-author), Published by Supreme Council for Research Centers and Institutes, 2007.

<!--Natural Flavours in Food and Drugs (Co-author), Published by Supreme Council for Research Centers and Institutes, 2007.

<!--Natural Colors in Food and Drugs (Co-author), Published by Supreme Council for Research Centres and Institutes, 2006.

<!--A guide to Medicinal Plants in North Africa, Published by IUCN Centre for Meditteranean Cooperation, Malaga (Spain), 2005.

conferences :

<!--3rd International Congreess Hidden Hunger, 20-22 March, 2017 in Stuttgart, Germany

<!--Oral presentations at 9th CMAPEEC, Plovdiv, Bulgaria 2016.

<!--The 61st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research which was held from September 1 -5, 2013 in Münster, Germany.

<!--المؤتمر الدولى العاشر حول "الآفاق المستقبلية للتنمية البيئية فى الوطن العربى ومواجهة التحديات"

والذى عقد فى شرم الشيخ فى الفترة من 21-24 ديسمبر 2013.

<!--Third World Organization for Women in Science (TWOWS), "TWOWS Fourth Assembly and International Conference: Women Scientists in a Changing World", 27-30 June 2010, Beijing, China.

<!--The Egyptian Second International Conference in Chemistry (The 18th Egyptian Chemical Conference), "Chemistry for Human Needs", 9-12th November 2009, Hurghada, Egypt.

<!--The 4th International Conference of Pharmaceutical and Drug Industries Research Division under the theme of "Research and Development in Drugs: Current Challenges", March 3-5/ 2009, NRC, Cairo, Egypt.

<!--The 2nd International Conference of the Arab Society for Medical Research under the theme of Medical Research in the Arab World "Modes of Collaboration and Development", November 11-13/ 2008, NRC, Cairo, Egypt.

<!--The 3rd International Conference of Pharmaceutical and Drug Industries Division under the theme of "Research and Development in Drugs: Future Trends", March 6-8/ 2007, NRC, Cairo, Egypt.

<!--The 55th Annual Congress of the Medicinal Plant Research which was held from September 2 -6, 2007 in Graze, Austeria.

<!--The 2nd International Conference of Pharmaceutical and Drug Industries Division under the theme of "Research and Development in Drugs: Future Trends", March 4-6/ 2005, NRC, Cairo, Egypt.

<!--The 46th Annual Congress of the Society for Medicinal Plant Research, Vienna, Austria, 1998.

<!--The 43rd Annual Congress of the Society for Medicinal Plant Research, Halle, Germany, 1995.

<!--Science 90, organized by the University of Wales, United Kingdom, 1990

<!--The Annual Congress of the arab Society for Medicinal Plant Research, Cairo, Egypt, 1988.

<!--The 33rd Annual Congress of the Society of Medicinal Plant Research, Regensburg, Germany, 1985.

LANGUAGES AND IT SKILLS

English: excellent command of English language

German: very good command of German language

IT Skills: excellent